KAJIAN HISTOPATOLOGI HATI KUCING YANG TERPAPAR FELINE INFECTIOUS PERITONITIS (FIP)
(Study of Histopathology Cat Liver with Infection of Feline Infectious Peritonitis (FIP))
GITA RIMA WIDYAMARTHA, EKOWATI HANDHARYANI, ADI WINARTO
ABSTRAK
Penelitian ini bertujuan untuk mengetahui gambaran histopatologi hati kucing yang terpapar Feline Infectious Peritonitis (FIP). Studi yang dilakukan ditemukan tiga ekor kucing, dari bulan Oktober tahun 2009 sampai dengan bulan Juni 2010, terdiagnosa terinfeksi FIP dan digunakan sebagai contoh kasus. Pengamatan pada gejala klinis dan histopatologi dilakukan berdasarkan prosedur rutin Laboratorium Patologi, Fakultas kedokteran Hewan, Institut Pertanian Bogor. Perubahan histopatologi pada hati dievaluasi menggunakan metode parafin dengan pewarnaan Hematoksilin-Eosin. Perubahan histopatologi diamati di bawah mikroskop cahaya. Hasil gambaran histopatologi semua hati yang dievaluasi ditemukan adanya kongesti general, peradangan multifokus, degenerasi, nekrosa, dan infiltrasi sel radang. Satu kasus ditemukan infeksi sekunder dengan koloni bakteri di dalam lumen vena. Evaluasi patologi anatomi ditemukan perubahan umum pada penderita FIP di beberapa organ seperti hydropsacites, ikterus, perihepatitis, pankreatitis, gastroenteritis dan peradangan granulomatus. Berdasarkan hal-hal tersebut dapat disimpulkan bahwa kongesti, degenerasi, dan nekrosa merupakan gambaran utama histopatologi hati yang terinfeksi FIP.
Kata kunci : FIP, hati, histopatologi, hydropsacites.
ABSTRACT
This study was aimed to know the histopathological aspect of Feline Infectious Peritonitis (FIP) that was focused on its liver. In this study three cats, from October 2009 until June 2010, that were diagnose suffering FIP were used as case samples. An observation on gross lesion and histopathology were done based on the regular protocol of Pathology Laboratory of Faculty of Veterinary Medicine, Bogor Agricultural University. The histopathological change of liver was evaluated with paraffin method and stained with Haematoxilin-Eosin dyes. The histopathological changes were observed under light microscope. The results showed that all evaluated livers were found in general congestion, inflammation multifocal, degeneration, necroses, inflamed cell infiltration. One of cases was found existing a secondary infection which appearing bacteria colonies in central vein lumen of lobules. In addition it also notes that pathological evaluation finding gave a general change of FIP on other organs such as hydropascites, icterus, perihepatitis, pancreatitis, gastroenteritis, and inflammation granulomatus in some organs. It could be conclude that congestion, degeneration and necroses are the main histopathological finding of the liver with FIP infection.
Keywords: FIP, histopathology, hydropsacites, liver